What is Cholesterol Made of in the Body?

By | July 21, 2019
How cholesterol is made in the body

By James Baggott Ph.D. 1997, 1998

What is cholesterol made of in the body? This 20-year old image shows Acetyl CoA is at the center of fat (lipid) metabolism (processing) inside your body. Acetyl CoA’s function is to mix all of the food together to make your energy, this process is shown as CO2 + H2O + energy (ATP), in the above diagram.

What is hidden in the ‘cholesterol not systemic inflammation causes heart disease,’ “brainwashing & spin,” is that triglycerides, phospholipids, eicosanoids, cholesterol, steroid hormones, and bile salts, are all essential fat-based substances. These are made together, during this metabolic process in the body. The ‘Acetyl CoA is a central intermediate in lipid metabolism’ diagram by James Baggott Ph.D. 1997, 1998, can be found here: Library Medical Utah Education Net biochem Fatty Acids.

PRECURSORS & PRODUCTS explanation  follows:

 Fat Based PRODUCTS Made by the Acetyl CoA Metabolic Process in the Body are:

#1. Triglycerides – are also called neutral fats. They have essential functions in your body and are located in storage sites all over your body. Their functions are to, insulate and protect vital organs and provide storage for energy. They are a raw ingredient building block. Their supplies are boosted by carbohydrates (sugars and starches) being stored as fat by insulin.

#2. Phospholipids – are located in your brain and nerve cells, plus are a construction ingredient of every cell in your body. They conduct electrical currents along nerves so you can feel sensation and touch.

#3. Eicosanoids (Prostaglandins) – are a vital part of your immune system. They control and, regulate up or down: child-birth contractions, inflammation, fever, blood pressure, and blood clotting.

#4. CO2 + H2O + energy (ATP) – make your body’s energy and is listed directly below Acetyl CoA.

#5. Cholesterol – is the main structural ingredient for: every cell in your body, your steroid sex hormones (testosterone, progesterone & estrogen), vitamin D and bile salts.

 This means cholesterol is made by your body at the same time as triglycerides, phospholipids, eicosanoids (prostaglandins), and your energy (CO2 + H2O + energy (ATP). This quote from the US National Library of Medicine agrees saying:

“Cholesterol is synthesized (processed) from Acetyl Coenzyme A in Three Stages. Acetyl CoA is the fuel for the citric acid cycle (The name of the energy-making process inside your body). This important molecule is formed from the breakdown of glycogen (the storage form of blood glucose), fats and many amino acids.

Nutrients names in this quote, which may need explaining are glycogen and many amino acids:

  • Glycogen is the name given to the chains of carbohydrate sugars in food & drinks, in your diet. Blood glucose is converted to glycogen when it is stored by insulin in your cells for future energy conversion.
  • Long chains of equal amounts of each Amino acid, forms protein your body can use. Protein is an essential structural material used in the body for: the hemoglobin in blood, collagen in tendons, bones & ligaments, keratin in hair & nails, elastin binds bones & ligaments together, actin & myosin in muscles, as enzymes for every biochemical reaction in your body, help balance & regulate pH, peptides & protein hormones help regulate metabolic activity such as insulin which regulates blood sugar levels, antibodies regulate your body’s defense system.

Food PRECURSORS: What is Cholesterol Made of in the Body?

PRECURSORS are the source ingredients the body uses to make cholesterol. In the feature diagram above, called ‘Acetyl CoA is a central intermediate in lipid metabolism’ by James Baggott PH.D. the PRECURSORS are: glucose & pyruvate, amino acids, fatty acids, and ketone bodies.

In the ‘Stages of Metabolism’ diagram, the PRECURSORS that make cholesterol are: Proteins, Polysaccharides (the name for the chains of carbohydrate sugars – glucose, fructose, & galactose), and Lipids (fats & oils). These are PRECURSOR source ingredients, processed and mixed together, by Acetyl CoA to make cholesterol.

Stages of Metabolism

How cholesterol is made in the body

Stages of Metabolism

Explanation of Stages of Metabolism

LOOK for the name Acetyl CoA in pink, with a pink downward arrow to Citric acid cycle, near the top and center of the green rectangle shape. – This shows you that Acetyl CoA is a vital part of the way your body’s metabolism makes your food to substances you need. Here is my explanation of Stage 1, Stage 2, and Stage 3:

  • STAGE 1 – Proteins, Polysaccharides (means many sugars – the chains of carbohydrate sugars listed here are Glucose, Fructose & Galactose) and Fats are food listed. When you eat at any time, all are mixed together and digested in your gastrointestinal tract.
  • STAGE 2 – This happens in your cells. Newly digested food (protein, carbohydrate, and fat) are made into smaller parts called molecules.
  • STAGE 3 This happens in the energy making part of your body called the mitochondria.

What is Acetyl Coenzyme A’s Function in The Body?

Acetyl Coenzyme A is a processor in your liver which converts nutrients. Its function is to carry out the inter-conversions of nutrients from: carbohydrates, fats, proteins, vitamins, and minerals from your diet, for use as energy. Your bodies essential fat-based substances: cholesterol, triglycerides, phospholipids, eicosanoids (prostaglandins), are made by this process. The shortened name of Acetyl Coenzyme A is Acetyl Co-A.

The Healthy Eating Plate: What is Cholesterol Made of in the Body

Now, let’s look at a Harvard Medical School version, of ‘Medical Dietary Advice’ called the Healthy Eating Plate. But first, refresh (re-think) your thinking and linking skills, re-read this quote from the US National Library of Medicine which says: “Cholesterol is synthesized (processed) from Acetyl Coenzyme A in Three Stages. Acetyl CoA is the fuel for the citric acid cycle (The name of the energy-making process inside your body). This important molecule is formed from the breakdown of glycogen (the storage form of blood glucose), fats and many amino acids.

LOOK at the Healthy Eating Plate. – Can you identify food sources of glycogen, fats, and many amino acids?

Food in the Healthy Eating Plate Are Mixed Together to Make Cholesterol

What is cholesterol made of in the body

The Healthy Eating Plate foods stored as glycogen or fat by insulin are: fruits, juice, vegetables, potatoes & French fries, whole & refined grains, pasta, rice, bread, cakes, cookies, sweets, low-fat products, dairy, sugar & natural sweeteners. According to my Human Anatomy & Physiology copy by Professor Elaine N. Marieb, beans lack two essential amino acids which are tryptophan and methionine. Have you LOOKED at bean labels to see how much sugar & carbohydrate they contain?

 The Healthy Eating Plate fat food are: canola oil, olive oil, butter, margarine, fake butter

The Healthy Eating Plate amino acids belong to the protein food group. From the diagram above these foods are: fish, poultry, red meat, cheese, bacon, cold cuts & processed meat

Let’s look at this quote one more time:

“Cholesterol is synthesized (processed) from Acetyl Coenzyme A in Three Stages. Acetyl CoA is the fuel for the citric acid cycle (The name of the energy-making process inside your body). This important molecule is formed from the breakdown of glycogen (the storage form of blood glucose), fats and many amino acids.

This quote from the US National Library of Medicine says cholesterol is made by the body when glycogen (carbohydrates), fat, and amino acids (protein) are mixed together for energy.

Does this help you understand how your body makes cholesterol from every food you eat in your diet?

Still wondering and challenged? Look at these evidence-based posts:

Conclusion: What is Cholesterol Made of in the Body?

Can you see where cholesterol is listed in this diagram?

How cholesterol is made in the body

By James Baggott Ph.D. 1997, 1998

This 20-year old image shows Acetyl CoA is at the center of fat (lipid) metabolism (processing) inside your body. 

It shows that the PRECURSOR source ingredients, to make cholesterol in the body are: glucose, amino acids, and fatty acids (fats & oils).

In the ‘Stages of Metabolism’ diagram, the PRECURSOR ingredients to make cholesterol are: Proteins, Polysaccharides (the name for chains of the carbohydrate sugar families of glucose, fructose, & galactose), and Lipids (fats & oils).

The Healthy Eating Plate foods stored as glycogen or fat by insulin are: fruits, juice, vegetables, potatoes & French fries, whole & refined grains, pasta, rice, bread, cakes, cookies, sweets, low-fat products, dairy, sugar & natural sweeteners

The Healthy Eating Plate fat food are: canola oil, olive oil, butter, margarine, fake butter

The Healthy Eating Plate amino acids belong to the protein food group. From the diagram above these foods are: fish, poultry, red meat, cheese, bacon, cold cuts & processed meat

Let’s look at this quote one more time Research says:

“Cholesterol is synthesized (processed) from Acetyl Coenzyme A in Three Stages. Acetyl CoA is the fuel for the citric acid cycle (The name of the energy-making process inside your body). This important molecule is formed from the breakdown of glycogen (the storage form of blood glucose), fats and many amino acids.

Do you ‘get’ that cholesterol is made in the body; from every food, you eat in your diet?

Please share what you think?

8 thoughts on “What is Cholesterol Made of in the Body?

  1. Kat

    I love this. It’s very technical, so a few bits have gone over my head, but I will simply take more time to reread the info. It’s so good to see this detail to describe what makes cholesterol in the body. We have been misled for so many years, This post is hugely valuable in being able to negate the myths, and show the truth about cholesterol. It does show how complicated it is, much more complicated that people with false opinions about not eating fats to prevent high cholesterol. I do love your final quote, that cholesterol is made from all food you eat!

    Reply
    1. Citizen Science by RJ

      Hello Kat,
      I do truly appreciate that you have obviously taken time to read my evidence based information. Many of our loved ones are soooo ill because they believe that healthy foods are low fat and are the ones produced by the powerful USA agricultural industries – corn, soy & modern wheat. And YES “Cholesterol is made from all the food we eat

      Citizen Science by RJ

      Reply
  2. Andrew

    So cholesterol is made from every food that we eat. If our body is making it, then we obviously need it. So why are we being told that cholesterol is bad for us?
    What does all of this information mean for us? How does knowing this benefit me?
    Cheers 🙂

    Reply
    1. Citizen Science by RJ

      Hello Andrew,
      Sadly, most people who live in Western Cultures, totally believe their doctors who recommend they are treated with: symptomatic treatment with pharmaceutical drugs, low fat diets containing the fruit, cereals & grains, starchy veg, and dairy. These food all contain families of sugars: glucose, fructose, glactose, & starch that trigger Inflammation. – Inflammation NOT Cholesterol Causes Heart Disease

      Citizen Science by RJ

      Reply
      1. Andrew

        Many thanks for this important information. It’s obvious that we all need to become more responsible for our own state of well-being, instead of relying on the ‘professionals’ to treat us with remedies that will not actually benefit our overall state of well-being.
        Have a great day 🙂

        Reply
    2. RJ

      Hi Andrew,
      Cholesterol medical drugs PROFIT is projected to reach $12.2 billion US dollars in 2018.
      BENEFITS: 1st you need to put into practice life-style and diet changes according to these 2 posts:
      https://cholesteroldetectives.com/review-the-pioppi-diet-a-21-day-lifestyle-plan-by-whistle-blowing-cardiologist/
      https://cholesteroldetectives.com/natural-anti-inflammatory-diet-plan-in-6-steps/
      ONLY THEN can you reduce your risks of: losing your waist size, gaining weight, needing high blood pressure medication, and dying of getting type 2 diabetes & heart disease complications!

      Citizen Science by RJ

      Reply

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