Does unresolved systemic chronic inflammation, or cholesterol, cause heart disease and stroke? Why does this WHO graph show heart (Ishaemic) disease and stroke as the leading cause of death, accounting for 15.2 million deaths in 2016, and the leading cause of death in the last 15 years?
Is Heart Heaths Advice Correct?
Heart Disease and Stroke Top Global Cause Death 2016
The following quote by a favored Human Anatomy and Physiology text says this about, what is cholesterol? – “Cholesterol is the raw ingredient for your sex hormones, testosterone, progesterone and estrogen. Without cholesterol your adrenal glands would fail. The pleasure of sex, relationships, and children would not exist. “Cholesterol is vital for homeostatis and it is essential for life” Says Chapter 2, Chemistry Comes Alive, Page 46-47, Tenth Edition, Human Anatomy & Physiology by Marieb and Hoehn.
What is Cholesterol-NEW Research Shows Cholesterol Makes Your Sex Hormones?
Lets look at two scientifically based diagrams, that helped me understand – ‘What is Cholesterol?’
The first diagram shows that cholesterol is the structural basis for the manufacture of your steroid sex hormones. This has been used to illustrate a difference, between pharmaceutically made steroid drugs (medications), and steroid fats naturally found in your body.
This means simple processes are turned into more complex processes.
Cholesterol is shown as the precursor of your steroid sex hormones where it links down to Pregnenolone, and then the Progesterone (the female sex hormone progesterone is made here). The Androgens make the male sex hormone Testosterone and the female Estrogens. Mineralocorticoids named in the center, regulate your body’s excretion of electrolytes in urine from your bladder via the kidneys. Glucocorticoids, the name on the far left regulates stress.
How Sex Hormones Are Made in Your Body
The www.researchgate.net/ diagram does not include the Fat Type of ‘Steroid’ in the explanation or title of “How Hormones Are Made in Your Body’ heading. This is why I have shown you the earlier diagram which is called “The Biosynthetic Relationship of Classes of Steroid Hormones and Cholesterol.”
A Diagram of Your Sex Hormones Showing Cholesterol as Their Parent ingredient
START with Cholesterol at the top, then link down to PROGESTERON – go to blue TESTOSTERONE, then ESTRADIOL (E2) and ESTRONE (E1) which are known as the Estrogens.
Steroids – A Type of Fat Naturally Found in Your Body
“Structurally, steroids differ quite a bit from fats and oils. Steroids are basically fat molecules made of four interlocking hydrocarbon rings. Like triglycerides, steroids are fat soluble and contain little oxygen. The single most important molecule in your steroid chemistry is cholesterol”
Says Chapter 2, Chemistry Comes Alive, Page 47, Tenth Edition, Human Anatomy & Physiology, Marieb and Hoehn.
“All steroids have the same basic skeletons and the chemical differences between them are slight.” But despite there being little chemical difference these steroid hormones are powerful and regulate a wide range of your body’s functions”
Says Chapter 18, Endocrine disease, Page 1048, 5th Edition, Clinical Medicine. Kumar & Clark, W.B. Saunders.
Cholesterol’s Family of Steroid Fats
What do HDL & LDL Lipoproteins Look Like?
Lipoproteins are made in your livers from triglycerides, protein, phospholipids, fat soluble vitamins, free cholesterol and cholesterol bound in fatty acids. This detailed image is from Mosby’s Medical Dictionary, 9th Edition.
HDL (high density lipoproteins) and LDL (low density lipoproteins) look like the image below.
Compare the diagrams for steroid fats, and the one of a lipoprotein.
NOW – Compare the diagrams for: How Steroid Fats Present in Your Body, and What so HDL & LDL lipoproteins Look Like.
- Do you wonder if there has been a mix-up, in defining Steroid Fats and Lipoproteins?
- Ask yourself – Why don’t the cholesterol steroid fats: cortisol, aldosterone, testosterone, progesterone and estrogen not look like a lipoprotein?
Low HDL and LDL Causes Early Death in Vulnerable Elderly Says Research
#1. RESEARCH SAYS – Your Grandparents live longer if their total cholesterol levels are higher than 189mg/dl (4.9 mmol/L) even when many other related factors were considered. THIS MEANS – Your grandparents die sooner, if their total cholesterol levels are lower than 189mg/dl (4.9mmol/L) even when many other related factors have been taken into account, this 2003 study found.
#2. RESEARCH SAYS – If your grandparents, or a parent, is chronically ill with heart failure, this 2000 research indicates, that they are less likely to survive if they have low blood concentrations of cholesterol.
#3. RESEARCH SAYS – Low total cholesterol, is a signal for higher deaths in elderly adults, who live in their own homes. This 12 year follow- up study of older adults reviewed research where the authors used different methods of analyzing the information. One researcher analyzed a group of home-dwelling elderly for 6 years and found more deaths occurred when their total cholesterol level was low. Overall results of this study reinforced the role that low total cholesterol levels were, as an indicator of higher death (mortality) rates when other health problems were excluded.
Low Cholesterol Levels Increases Risk of Parkinson’s
And paradoxically, high total cholesterol levels decrease your brains risk of developing Parkinson Disease. Cholesterol is a vital structural component of the cell membranes of your brain, and the entire nervous system located in your brain. The Rotterdam Study involved 6465 people aged over 55 years. At the start of this study they were all examined – then were re-examined 9.4 years later. It was discovered that higher total cholesterol levels, were associated with a lower number of the women members of the group developing Parkinson’s disease:
The Rotterdam Study involved 6465 people aged over 55 years. It was published in The Oxford Academic American Journal of Epidemiology 2006. At the start of this study they were all examined – then were re-examined 9.4 years later. It was discovered that higher total cholesterol levels, were associated with a lower number of the women members of the group developing Parkinson’s disease.
Here are the surprising findings of the Rotterdam study:
TOTAL CHOLESTEROL LEVELS:
- BELOW 6.1 mmol/L (110 mg/dl) increased Parkinson risk by 58%
- BETWEEN 6.1 – 6.8 mmol/L (110 – 122 mg/dl) increased Parkinson risk by 46%
- BETWEEN 6.8 – 7.0 mmol/L (122 – 126 mg/dl) increased Parkinson risk by 16%
Are HDL and LDL Part of Your Innate Immune System?
It has been wrongly thought the sole purpose of HDL (high density lipoproteins), LDL (low density lipoproteins) and VLDL (very low density lipoproteins) in your blood was to transport fats.
Here is the evidence of this research published in 2010:
Lipoproteins seem to have been wrongly called cholesterol by the businesses of healthcare
Unbelievably plasma (blood) lipoproteins are important parts of your immune system – your innate immune system.
Your innate immunity is your body’s natural immune system. It is the FIRST LINE or FRONT LINE of defense soldiers put into action by your immune system.
RESEARCH FOUND THAT:
Lipopolysaccharides (LPS) are signal like attachments, attached to bacteria, virus and parasites. LPS warn your first line of defense immune systems soldiers, that your body has harmful invaders.
THE RESEARCHERS WHO DISCOVERED THIS IGNORED INFORMATION :
Caradonna L, Amati L, Magrone T, Pellegrino NM, Jirillo E, Caccavo D. Enteric bacteria, lipopolysaccharides and related cytokines in inflammatory bowel disease: biological and clinical significance. J Endotoxin Res. 2000;6(3):205-14.
Medical researchers have detected lipopolysaccharides and lipoteichoic acid in the blood of patients who have abnormal gut bacteria (microflora) or increase permeability of the intestinal mucosa. This is commonly known as leaky gut syndrome. Research has found lipoproteins bind to lipopolysaccharides (LDS) thereby preventing attacks and neutralizing harmful invaders.
Does this research mean cholesterol, or more correctly lipoproteins, are part of your first line of defense, immune systems soldiers and not the cause of heart disease?
CONCLUSION: What is Cholesterol-NEW Research
- Why is Heart Disease and Stroke the Leading Cause of Death for the Last 15 years?
- Why is Heart Disease and Stroke the #1 KILLER in 2016?
Once again look at the WHO (World Health Organizations graph showing the Top 10 causes of death globally. Ischaemic (Ischemic) heart disease and Stroke at the top 2 lines. Ishaemic means death from lack of oxygen to your heart.
Cholesterol is a vital structural component of the cell membranes of your brain, and the entire nervous system located in your brain. LEARN about:
You are so welcome here. Has this evidence based information shocked you, or clarified some niggles you’ve had in your mind? What do you think?