What is Inflammation in the Body?

By | March 31, 2019

Inflammation in the body is a natural response to injury. Its function, as part of your metabolism is to heal wounds. But as chronic inflammation, it has a role in many deadly diseases, including Alzheimer’s, arthritis, cancer, diabetes, heart disease and possibly depression say the John Hopkins Health Review.

Inflammation is triggered naturally, by your immune system; when your body is injured by trauma, intense heat, irritating chemicals, or infection by viruses, fungi, or bacteria.

Without inflammation as a function of your immune system, burns, throat infections, sprains, and cuts would fester and spread quickly through your body and never heal.

What is Acute Inflammation in the body?

Acute inflammation is a short term local function which is triggered naturally, by your immune system. This happens in and around the exact location of: your grazed knee, your sore throat, your broken leg, or your cut finger. This initial injury starts the acute inflammation process in your body.

During an acute inflammation event in your body, five chemicals called – Inflammation Chemicals, are released into your blood stream. Table 21.2, Chapter 21, Immune System: Innate and Adaptive Body Defenses page 776 of Marieb and Hoehn’s, Human Anatomy & Physiology lists these ‘five inflammation chemicals:

Five Inflammation Chemicals Released into Your Blood Stream

  1. Histamine
  2. Complement
  3. Kinins
  4. Prostaglandins
  5. Cytokines

When your immune system releases the inflammation chemicals (histamine, complement, kinins, prostaglandins and cytokines) into your blood stream this starts the acute inflammation process. – Then, tiny blood vessels called arterioles dilate, and even smaller vessels called capillaries increase permeability. – This lets your white blood cells (Neutrophils, monocytes and lymphocytes) travel to the injured area. – The increased blood flow to your injury creates HEAT & REDNESS. Capillaries leak fluid into the area around the injury. PAIN, SWELLING & temporary LOSS of FUNCTION occur. – The heat increases the metabolic rate of cells, and lets clotting protein and fibrin start the repair process. – The ultimate goal of an acute inflammation response is to clear the area of pathogens, dead tissue cells and any debris so that tissue can be repaired. – Once this has happened healing usually occurs quickly and is beneficial.

Swelling (edema) may seem detrimental, it isn’t. When swelling occurs, the surge of protein-rich fluids into the tissue spaces sweeps foreign material into lymphatic vessels for processing in the lymph nodes. Swelling also delivers important proteins such as complement and clotting factors to the spaces between blood vessels called interstitial spaces says the Human Anatomy & Physiology by Marieb and Hoehn, Chapter 21, The Immune System: Innate and Adaptive Body Defenses, page 771-806, Tenth Edition.

Acute Inflammation in the Body Signs and Symptoms

Five signs and symptoms of acute inflammation are:

  1. Redness,
  2. Heat,
  3. Swelling,
  4. Pain and
  5. Loss of function.

Examples of loss of function include; not being able to move an inflamed joint properly, having a worse sense of smell during a cold, or finding it more difficult to breath when you have bronchitis, according to the US National Library of Medicine.

What Happens When Acute Inflammation Fails to Heal in the Body?

This becomes unresolved chronic inflammation and happens when your body’s power of correction goes wrong and works against you. Here are two examples of what happens when acute inflammation fails to heal in the body.

Inflammation is the process that causes cholesterol to be put into the walls of your arteries (blood vessels) and forms the buildup of plaque say the US National Library of Medicine.

Blood clotting within your hearts arteries walls is known as atherothrombosis. It is driven by unresolved inflammation. This blood clotting within your hearts artery walls (atherothrombosis), is the real killer, say the British Journal of Sports Medicine.

What is Chronic Inflammation in the body?

Unlike acute inflammation which is resolved and healed, chronic inflammation in the body is unhealed and unresolved. Chronic inflammation is not a specific disease but a mechanistic process (system of moving parts). The diseases associated with chronic inflammation are multiple and include:

  1. CVD (cardiovascular or heart disease
  2. Diabetes
  3. Malignancy (cancer)
  4. Auto-immune disease
  5. Chronic hepatic (liver)
  6. Renal (kidney) disease
  7. Inflammatory bowel disease

Chronic inflammation is a slow, long-term inflammation lasting for prolonged periods of several months to years says the US National Library of Medicine.

Chronic inflammation is through-out your body, it is therefore a type of systemic inflammation and can contribute to the development of disease, according to the summary in the John Hopkins Health Review.

How Does Chronic Inflammation Affect the Body?

With high blood pressure (hypotension), which is linked to arterial stiffness (hardening of your arteries), inflammation may play a role in the progression of your arteries getting worst, say the Journal of the American Heart Association.  Chronic inflammation (in blood vessel walls, the endothelium) is the common link in the development of hypertension (high blood pressure) in the elderly, said the American Journal of Hypertension way back in 2003.   Compelling evidence suggests that high blood pressure is a chronic inflammatory disease, which is linked to the development of heart disease say the US National library of Medicine.

 Hypertension is one of the most important contributors to atherosclerosis (heart disease and strokes) development in your body.

This means that when your blood pressure goes up, your body is warning you that chronic inflammation is silently damaging the blood vessel walls (endothelium) everywhere.

WARNING – Has your doctor told you that hypotension medication forces your blood pressure down, but cannot heal or prevent the damage that chronic inflammation is continually doing to your artery and capillary walls (blood vessels)?

MORE ON – How Chronic Inflammation Affects the Body

Chronic inflammation in the body is a mechanistic, total body wide process. Chronic inflammation is also called a systemic process by the John Hopkins Health Review. 

Here are eight more ways of chronic inflammation affects your body according to Oncotarget in an open source site and the US National Library of Medicine in 2018. They have made this link unavailable (https://www.ncbi.nlm .nih.gov/pmc/articles/PMC5805548/) But here is the vital 2018 information:

Here is their list of 8:

  1. Inside your heart
  2. Inside your pancreas
  3. Inside your liver
  4. Inside your kidneys
  5. Inside your lung
  6. Inside your brain
  7. Inside your intestinal tract
  8. Inside your sex and reproductive organs

Chronic inflammation continues as microscopic damage deep inside your body’s organs long before you are given a name for your health problem.

The Western Medical Systems failure to investigate root causes means you are always incorrectly assessed. And vital anti-inflammatory diets & tests are never considered for you., Plus, you suffer. You suffer with a swollen painful, dysfunctional metabolism which is medicated up-to-your-eyeballs.

Early Symptoms of Chronic Inflammation in the Body

Compelling evidence suggests that high blood pressure is a chronic inflammatory disease, which is linked to the development of heart disease say the US National library of Medicine.

Some other common signs and symptoms that the body develops when unresolved inflammation is ravages you, say the US National Library of Medicine are:

  1. Continual Body pain
  2. Constant fatigue and insomnia (no energy and not able to sleep)
  3. Depression, anxiety and mood disorders (stress)
  4. Frequent infections
  5. Weight gain
  6. Gastrointestinal complications like constipation, diarrhea, and acid reflux

I want to add ‘Swelling as #7’ in the above list And ‘Increasing fluid retention as #8’ in the above list of common symptoms of chronic inflammation, and not a sign of aging

Do You Want to Die of a Chronic Inflammatory Disease?

This World Health Organization (WHO) graph identify diseases that develop due to unresolved inflammation in the body. These become chronic inflammatory diseases, which are managed by pharmaceutical drug therapy. Modern Western Medicine does investigate root cause or prevention strategies. Is a swollen, painful, managed, death, going to be yours?

Death Numbers from Top 8 Chronic Inflammatory Diseases in the Body Say WHO

8 out of 10 (blue) in the upper-middle-income countries in this WHO 2016 graph represent the number of deaths caused by chronic inflammatory disease. The rust color line represents Lower respiratory infections, a communicable disease. And the green line, represents Road injury deaths.

Non communicable diseases (NCDs), are also known as chronic or systemic inflammatory diseases. Cardiovascular diseases such as heart attacks and strokes, where high blood pressure is an early warning of chronic inflammation, are the leading causes of death; – Cancers, Chronic respiratory diseases (asthma & obstructive pulmonary diseases), Diabetes, Alzheimer’s and Dementia s are in the Top 10 causes of death in upper-middle-income countries say this World Health Organization (WHO) in 2016.

What Triggers Chronic Inflammation in the Body?

The nutrition we get from food: builds wellness and longevity, or gradual declining health problems which develop into disease. Nutrition from modern day: low fat, baked, processed, food contain a lot of refined carbohydrate (sugars & starches) and vegetable seed oils from the omega-6 families; but no saturated fat.

Saturated Fat Does NOT Trigger Inflammation in the Body Says Cardiologist

British Cardiologist Dr Aseem Malhotra slams ‘Government Dietary Guideline Advice’ during a Parliamentary speech in the House of Commons saying-

“Saturated fat does not clog the arteries; coronary heart disease is a chronic inflammatory condition, the risk of which can be effectively reduced from healthy lifestyle intervention.” The evidence, this honest Cardiologist, and his unbiased medical academic fellow researchers have found is that, Saturated FAT DOES NOT CLOG ARTERIES!

View presentation here: https://www.youtube.com/watch?v=HvMFj6NxPGI

WHO ARE THEY? –   Follow the evidence of where most deaths occur in the graph from the WHO. – Death Numbers from Top 8 Chronic Inflammatory Diseases in the Body.

Their laser like business focus, of medicine is profit, and pharmaceutical procedures and drugs, over investigating root causes. –  Unbelievably, they are untrained in how the foods you eat and your diet, effect your body’s metabolism.

Here is the evidence of at least two foods which trigger chronic inflammation in the body.

Coronary Artery Plaque Image by Cardiologist Dr Aseem Malhotra – https://www.youtube.com/watch?v=HvMFj6NxPGI

The evidence Cardiologist Dr Aseem Malhotra and Dr Zoe Harcombe found, that the root causes of coronary artery plaque are:

  • Excess fructose and refined carbohydrates (located in the white area bottom left).
  • Sub optimal omega 3 (located in white area bottom right).
  • Too much omega 6 (located in white area bottom right).
  • And Other factors.

The list of 4 contain arrows that point into the pale yellow or cream box the titles – Insulin Resistance and/or Systemic Inflammation which is also known as chronic inflammation in the body.

  1. Insulin Resistance is a very confusing name. What it really means is that your carbohydrate and sugar based diet, forces your body to continually produce the hormone insulin. The name, Insulin Resistance, misrepresents the fact, that the ‘beta cells’ in your pancreas have been BURNT OUT by the carbohydrate families of sugars & starches you’ve been recommended to eat by government dietary guidelines. Then, doctors managed you for the rest of your declining sick life, with diabetes medication. A point I find interesting is this – The estimated cost to public health, but income for pharmaceutical businesses in 2018 for the US is $327 billion say the American Diabetes Association.

Are you confidently following the glycemic index system of ranking foods, according to the amount of sugar they contain, in the belief that they are harmless?

Number of Teaspoons of Sugar in Food Recommended by Government Food Guidelines Advice

Except for eggs, every food in the above list are families of carbohydrates, sugars and starches trigger insulin. These are the food which cause BURN OUT of the beta cells of your pancreas. Then your pancreas is unable to make insulin. PLUS, for some reason you are diagnosed with insulin resistance or metabolic syndrome, but NOT chronic inflammation in the body.

Can you measure your A1C (Glycated hemoglobin) or HbA1C (Glycated haemoglobin) percentage? If you can measure your A1C – HbA1C this means you are following the standard recommended Western Diet Guidelines. These contain at least 70% of carbs (sugars & starches) in each serve suggestion.

IMPORTANTLY, it means that the blood glucose from carbohydrates sugars and starch are attacking (attaching themselves to) your red blood cells. This damages your artery walls. (1) (2) Too much carbohydrates in your diet are one of the root cause of chronic inflammation in the body.

IMPORTANT, your AIC percentage ought to be 0% to be NON DAMAGING TO BLOOD VESSEL WALLS. 

  1. Sub optimal omega 3, and too much omega 6 vegetable seed oils in cooking, and as an ingredient in most processed and baked foods, means your body has no choice but to use it for nutrition. The imbalance of omega 6 to omega 3, trigger inflammation inside the cells or your body. A dangerous imbalance can be found in blood cells when an omega 3 blood test is carried out. According to British Cardiologist Dr Aseem Malhotra in his book The Pioppi Diet our hunter gather ancestors had a ratio of 1:1 (Omega 6: Omega 3). Evidence in The Pioppi Diet shows:
  • Modern Western Diet – 25:1
  • Rural India – 5-6:1
  • Urban India – 40:1

 Chronic Inflammation Treatment in the Body by Western Medicine

“Currently there are no prescription drugs that specifically target chronic inflammation.” “Basic science hasn’t yet answered the major questions about inflammation” says Michelle Petri, a rheumatologist and director of the John Hopkins Lupus Center, in The John Hopkins Health Review.

Modern Western Medicine treats chronic inflammation with non steroidal anti-inflammatory drugs (NSAID) which produce their therapeutic activities through inhibition of cyclooxygenase (COX), the enzyme that makes prostaglandins) PGs). Say the US National Library of Medicine in this research. 

Tests for Chronic Inflammation in the Body

STEP 1. Weight to Height Ratio. Measure your waist and height. Your waist should be less than half of your height

IMAGE of Weight to Height Ratio by Cardiologist Dr Aseem Malhotra https://www.youtube.com/watch?v=HvMFj6NxPGI

STEP 2. Decode the content of your red blood cells. Find out if there are pro inflammatory fats in your blood cells: The Trans-fat index, the Omega-6: Omega-3 Ratio, and an Omega-3 Index deficiency test, are baseline tests if you want to investigate, where inflammation triggers are coming from in your body.

STEP 3 & 4. Know your numbers for Fasting Insulin and Hemoglobin A1C-HbA1C…!

Excess fructose and refined carbohydrates cause Insulin Resistance or beta cell BURNOUT of your pancreas by continually forcing insulin to be made by your body. This forces blood glucose to be attached to your red blood cells when you have too much sugar in your diet. Are these two things happening inside your body? Get your Fasting Insulin Test here and Hemoglobin A1C-HbA1C Test here.

A Solution to Reduce Chronic Inflammation in The Body?

Cardiologist, Dr. Asseem Malhotra found: too much fructose & refined carbohydrates and too much omega-6 vegetable oils drive inflammation inside your body. The following book contains evidence, and a lifestyle and diet plan as solutions.

Bust Myths in Todays Weight Loss & Health Industries

Anti-Inflammatory Diet Meal Plan, Authentic Mediterranean Lifestyle & Diet, based on a Village that has No Gym, No Supermarket, and Enjoy a Glass of Wine Each Evening.

The Pioppi Diet A 21 – Day Lifestyle Plan,  By Dr Aseem Malhotra & Donal O’Neill – Lose weight, feel great and drastically reduce your risk of type-2 diabetes and heart disease

  • We are not being told the truth about our health.
  • We’re told to avoid saturated fats, we’re marketed health food that is laden with sugar and we’re encouraged to pound out miles at the gym. However, our chance of getting obese are increasing – raising our risk of type-2 diabetes, cancer, dementia and heart disease.
  • In just 3 weeks, The Pioppi Diet will help you make simple achievable and long-lasting changes to how you eat, sleep and move – changes that all of us, no matter how busy we are, can make.

Conclusion to What is Inflammation in the Body?

Why is failed science continually reinforced, and profit put before health? Why is the World Health Organization (WHO) seemingly powerless, and the Top 8 Chronic Inflammatory Diseases graph the result?

Now I would like to here from you. What do you think?


14 thoughts on “What is Inflammation in the Body?

  1. Cherry Parks

    I don’t want to die. I suffer from 2 of the things you talk about. Hypertension and newly diabetic. I know dropping about 30 pounds and I should be cleared from this. However my anti-histamine blockers stopped working at 28. I am allergic to stuff like grass, trees so I take something for that. I am going to look into the Poppi Diet. See what all it say. Thank you for your informative information.

    1. Citizen Science by RJ

      I’m so please that you’ve found this post Cherry
      Read everything in the Pioppi Diet – use it as a life changing moment.
      But importantly use The Pioppi Diet to to regain your health & ENJOY your journey

  2. Kelly

    There is a lot of good information in here regarding inflammation. Thank you for posting. It is definitely food for thought regarding how we need to care for our bodies. Well done!

  3. Helen

    This is a great post which I enjoyed reading. I’ve learned quite a few things from it too.
    One thing that I can relate to is following a low sugar diet, which is something I have recently switched to.
    I was amazed at how much hidden sugar is found in processed foods, once I started looking at the labels.
    I have found many low sugar alternatives and I’ve started eating more nuts, cheese and eggs.
    I’m feeling the benefits already and my kids (who are also following a low sugar diet) have shown much improvement in their behaviour and concentration at school.
    I’m hoping this will benefit my health overall, as there is a history of high cholesterol in my family.
    Thanks for a great article.

    1. Citizen Science by RJ

      This is such great news that you’ve noticed a difference in your children s behavior and wellbeing by having a low sugar diet.
      I’m pleased that you were able to learn something from the post.

  4. Jean

    This is the easiest to read and best information I have ever seen on this subject. I have arthritis in my dominant hand and in the morning, it is swollen and stiff. Within a couple hours, it is back to normal but it scares me a bit so I am reading everything I see about inflammation. The details are enlightening and the misinformation is shocking. I have bookmarked your site and will read more of your posts when I have finished my training.

    1. citizensciencebyRJ

      Jean, Thankfully you’ve found my site and have found the evidence helpful.
      Unbelievably, dis-inflammation is endemic in our medical healthcare industry. This increases, our sickness and the profits of their industry.

  5. Bronwyn Fletcher Evans

    Great article. Thank you for sharing. This is a very simplified article that I can actually understand. I am not unintelligent but sometimes find the medical terminology a bit too much for me to understand. This article I understand.

    1. Citizen Science by RJ

      Hello Bronwyn,
      Thank you for connecting. Like you I’ve had huge challenges understanding complicated medical terminology. I’m so pleased that I’ve been able to help you feel as though you understand inflammation in the body.

  6. Mark Bailey

    Thanks for sharing lots of great information. I am a lot better educated on the causes of inflammation and it was interesting to read about the pioppi diet.

    1. Citizen Science by RJ

      Hi Mark,
      I’m pleased you notice the Pioppi Diet. It is a reference I’ve used to help us understand how we all underestimated inflammation in the body is. It is written by a British Cardiologist and has helped me a lot. Are you going to get a copy of the Pioppi Diet?

  7. Timothy Guth

    This has open my eyes on “Pioppi Diet”
    Also laid out a lot of great, Information.
    Now I have a better understanding on this.
    As I am not much on the medical terminology but you have shine a light on this.

    1. Citizen Science by RJ

      Hi Timothy,
      GREAT NEWS, that I’ve opened your eyes on the ‘Pioppi Diet.’
      And also that my explaining complicated medical terminology has ‘shine a light’ for you.
      The secrets medical terminology has hidden from us has been hidden too long.
      Thanks for stopping by…


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